Provigil (modafinil) is a drug that advances attentiveness. It is thought to work by adjusting the normal synthetic substances (synapses) in the cerebrum. Provigil is utilized to treat unnecessary languor brought about by rest apnea, narcolepsy, or move work rest issue.
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Take Provigil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Modafinil may be habit-forming. Never share Provigil with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Provigil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
You may take the tablet with or without food.
Provigil is usually given for 12 weeks or less.
If you are taking Provigil to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to a mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction.
Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and Provigil may be necessary to best treat your condition.
Provigil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor’s instructions about all your other treatments for this disorder.
Call your doctor if you continue to have excessive sleepiness even while taking this medicine.
Taking Provigil does not take the place of getting enough sleep.
Store at room temperature away from moisture and heat.
Keep track of the amount of medicine used from each new bottle. Modafinil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Usual Adult Dose for Narcolepsy:
200 mg orally daily in the morning
Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome:
200 mg orally daily in the morning
Usual Adult Dose for Shift Work Sleep Disorder:
200 mg orally daily one hour prior to the start of the work shift
Usual Pediatric Dose for Attention Deficit Disorder:
Not FDA approved.
Reports of serious dermatologic adverse effects and psychiatric events has resulted in the FDA’s Pediatric Advisory Committee unanimously recommending that a specific warning against the use of modafinil in children be added to the manufacturer’s labeling; use only if first- and second-line treatments have failed and the benefits outweigh the risks.
Children less than 30 kg: 200-340 mg once daily
Children more than 30 kg: 300-425 mg
Randomized, double-blind, placebo-controlled pediatric studies have utilized an 85 mg film-coated tablet (currently not commercially available) to provide these dosages. All studies utilized a titration method but varied the length of titration (3 weeks vs 7-9 days); clinical improvement was noted earlier in the shorter titration period.
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid other dangerous activities until you know how Provigil will affect your level of wakefulness.
Avoid drinking alcohol while taking modafinil.
Get emergency medical help if you have signs of an allergic reaction to Provigil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Provigil can cause skin reactions that may be severe enough to need treatment in a hospital. Stop taking this medicine and get emergency medical help if you have:
Stop using Provigil and call your doctor at once if you have:
Common Provigil side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Other drugs may interact with modafinil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
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